Biocatalytic potential of thermophilic bacteria and actinomycetes

Thermophilic organisms have been less explored due to the difficulties in isolation and maintenance of pure culture. Therefore, it remains to explore their diversity and biotechnological potential from majority of the thermal habitats. As a consequence of growth at high temperature and unique macromolecular properties, thermophiles can possess high metabolic rates, physically and chemically stable enzymes and lower growth but higher end product yields than similar mesophilic species. In addition, cultivation of thermophiles at high temperature is technically and economically beneficial as it reduces risk of contamination and viscosity which leads to high degree of substrate solubility.